The Pap test is an important part of the cervical cancer screening process. 60-80% of women diagnosed with cervical cancer have not had a Pap test within 5 years of their diagnosis. For sexually active women, getting a Pap smear on a regular basis is the best way to manage the risk of cervical cancer.
Nearly 30% of women age 14-59 are positive for one or more strains of HPV.  Not all HPV infections, however, will cause the DNA damage that can lead to cervical cancer, and many HPV-positive women clear their infection within 2 years without developing cancer. It is important to identify those women who are at risk for developing cervical cancer.
While getting tested for HPV is useful, HPV typing only evaluates the presence of certain strains, whereas all strains have the possibility of leading to irreversible DNA damage in the woman’s genome. Furthermore, HPV typing doesnâ€™t have any predictive value with respect to the risk of progression to cancer.
Why is the FHACTÂ®Â testing important?
FHACTÂ® assesses the presence of DNA damage caused by HPV infection, and may therefore aid in identifying women with a higher risk of progression to cervical cancer.
FHACTÂ® is useful for women who are high risk HPV positive with normal cytology, as well as women with LSIL or ASCUS cytology.
FHACTÂ® is performed on leftover liquid cytology (Pap smear) specimen. Therefore, it is non-invasive, and doesnâ€™t require an additional office visit. The result is generally available within 7 days.
Please ask your doctor about FHACTÂ® at your next appointment or annual exam.